Dewald J P, Sheshadri V, Dawson M L, Beer R F
Sensory-Motor Performance Program, Rehabilitation Institute of Chicago and Department of Physical Medicine and Rehabilitation, Northwestern University Medical School, Chicago, Illinois, USA.
Top Stroke Rehabil. 2001 Spring;8(1):1-12. doi: 10.1310/WA7K-NGDF-NHKK-JAGD.
Clinically, upper-limb discoordination after stroke is evident in the form of stereotypic movement patterns that reflect a loss of independent joint control. These movement abnormalities, in conjunction with our recent quantitative findings under isometric conditions, provide evidence for an impaired capacity to generate certain muscle coactivation patterns in the impaired limb. In this article, we examine the parallels that exist between coordination disturbances observed under isometric and movement conditions. Our results suggest that discoordination in stroke may largely represent a manifestation of additional neural constraints on motor outflow. The neurotherapeutic implications of our findings are discussed.
临床上，中风后上肢运动失调表现为刻板的运动模式，这反映了独立关节控制能力的丧失。这些运动异常，结合我们最近在等长收缩条件下的定量研究结果，为患侧肢体产生特定肌肉共同激活模式的能力受损提供了证据。在本文中，我们研究了等长收缩和运动条件下观察到的协调障碍之间的相似之处。我们的结果表明，中风后的运动失调可能在很大程度上代表了对运动输出的额外神经限制的一种表现。我们讨论了研究结果对神经治疗的意义。
