[Genetic studies in allergology].

A wide application of molecular biology methods provided the basis for genetic studies of complex diseases, like allergic diseases. Analysis of genetic predisposition for these diseases should be performed at the level of individual phenotype, atopic background and differences in severity of individual diseases. The most frequently used methods of identification of disease-causing genes include positional cloning and candidate gene studies. In spite of huge advances in genetic studies the genetic predisposition for allergic diseases has not been fully elucidated.