Chiron Bruno, Laffon Marc, Ferrandière Martine, Pittet Jean-François
Department of Anesthesia, University Hospital, Pointe-a-Pitre, West French Indies.
Can J Anaesth. 2003 Oct;50(8):812-4. doi: 10.1007/BF03019377.
To report the injection of a colloid in the epidural space as an alternative to an epidural blood patch in a woman with sickle cell disease.
A Cesarean delivery was performed under spinal anesthesia in a 32-yr-old woman with severe sickle cell disease and a past medical history of vaso-occlusive crisis. In the postoperative period, the patient complained of postdural puncture headache resistant to symptomatic treatment. Because there were no data concerning the safety of a blood patch in this condition, a colloid (a modified fluid gelatin heated to 37 degrees C) was injected in the epidural space instead of blood. Headaches decreased immediately after the epidural injection of the colloid and disappeared totally within 12 hr.
Data concerning the safety of epidural blood patches in patients with sickle cell disease are lacking. Injection of colloids in the epidural space could be an alternative.
报告在一名镰状细胞病女性患者中，向硬膜外间隙注射胶体作为硬膜外血贴替代方法的情况。
一名32岁患有严重镰状细胞病且有血管闭塞性危机病史的女性在脊髓麻醉下接受剖宫产。术后，患者抱怨硬膜穿刺后头痛，对症治疗无效。由于在此情况下缺乏关于血贴安全性的数据，因此向硬膜外间隙注射了一种胶体（加热至37摄氏度的改良液体明胶）而非血液。硬膜外注射胶体后头痛立即减轻，并在12小时内完全消失。
缺乏关于镰状细胞病患者硬膜外血贴安全性的数据。向硬膜外间隙注射胶体可能是一种替代方法。
