Ko Hyang-Mi, Jhu Im-Kwan, Yang Seung-Ho, Lee Jae-Hyuk, Nam Jong-Hee, Juhng Sang-Woo, Choi Chan
Department of Pathology, Chonnam National University Hospital, Gwangju, Republic of Korea.
Acta Cytol. 2003 Sep-Oct;47(5):727-32. doi: 10.1159/000326596.
To evaluate the accuracy of fine needle aspiration (FNA) of thyroid lesions at our institution and to ascertain its usefulness in determining the therapeutic approach.
The authors reviewed the results of 1,613 cases of FNA cytology of thyroid nodules performed from 1999 to 2001 at the Department of Pathology, Chonnam National University Hospital. Cytologic diagnoses were compared with histologic diagnoses in 207 cases that included both FNA and thyroid surgery.
The sensitivity for the detection of neoplasms (carcinoma and follicular adenoma) was 78.4% and the specificity 98.2%. A false positive diagnosis was made in 1 case (1.8%) and false negative ones in 28 cases (21.5%). The diagnostic accuracy was 84.4%, with a positive predictive value of 99.0% and negative predictive value of 66.3%. The predictive value of a cytologic diagnosis was 100% in papillary carcinoma.
FNA is a useful test in determining the therapeutic approach of thyroid lesions.
评估我院甲状腺病变细针穿刺抽吸术（FNA）的准确性，并确定其在确定治疗方法中的实用性。
作者回顾了1999年至2001年在全南国立大学医院病理科进行的1613例甲状腺结节FNA细胞学检查结果。在207例同时进行了FNA和甲状腺手术的病例中，将细胞学诊断与组织学诊断进行了比较。
肿瘤（癌和滤泡性腺瘤）检测的敏感性为78.4%，特异性为98.2%。假阳性诊断1例（1.8%），假阴性诊断28例（21.5%）。诊断准确率为84.4%，阳性预测值为99.0%，阴性预测值为66.3%。细胞学诊断对乳头状癌的预测值为100%。
FNA是确定甲状腺病变治疗方法的一项有用检查。
