Farinola Maryam A, Lawler Leo P, Rosenthal Dorothy
Departments of Pathology and of Radiology and Radiological Science, Johns Hopkins Hospital, 600 North Wolfe Street, Path 406, Baltimore, Maryland 21287, USA.
Acta Cytol. 2003 Sep-Oct;47(5):787-91. doi: 10.1159/000326607.
Plasmacytoma of the bladder is a rare but important entity. We report a case of plasmacytoma of the bladder that was diagnosed by urinary cytology.
A 71-year-old male with a history of multiple myeloma presented in renal failure. Renal ultrasound revealed right-sided, moderate hydronephrosis with a 4 x 4-cm, posterolateral, obstructing mass. Magnetic resonance imaging demonstrated a bladder mass involving the bladder base, right lateral wall and dome with extension into the perivesical tissues on the right. The mass showed a moderate degree of enhancement following intravenous gadolinium administration. Urine cytology was performed to evaluate for bladder carcinoma or other malignancies besides plasmacytoma. The specimen was signed out as multiple myeloma of the bladder. Cystoscopy and biopsy were subsequently performed on the bladder mass. The diagnosis of plasmocytoma was made, confirming the urine cytology diagnosis.
Urinary cytology can be a diagnostic tool for plasmocytoma involving the bladder.
膀胱浆细胞瘤是一种罕见但重要的疾病。我们报告一例通过尿液细胞学诊断的膀胱浆细胞瘤病例。
一名71岁男性，有多发性骨髓瘤病史，因肾衰竭就诊。肾脏超声显示右侧中度肾积水，伴有一个4×4厘米、位于后外侧的阻塞性肿块。磁共振成像显示膀胱肿块累及膀胱底部、右侧壁和顶部，并延伸至右侧膀胱周围组织。静脉注射钆后，肿块显示中度强化。进行尿液细胞学检查以评估除浆细胞瘤外的膀胱癌或其他恶性肿瘤。标本诊断为膀胱多发性骨髓瘤。随后对膀胱肿块进行了膀胱镜检查和活检。确诊为浆细胞瘤，证实了尿液细胞学诊断。
尿液细胞学检查可作为诊断累及膀胱的浆细胞瘤的一种工具。
