Gobbelé R, Schürmann M, Forss N, Juottonen K, Buchner H, Hari R
Brain Research Unit, Low Temperature Laboratory, Helsinki University of Technology, P.O. Box 2200, FIN-02015 HUT, Espoo, Finland.
Neuroimage. 2003 Sep;20(1):503-11. doi: 10.1016/s1053-8119(03)00312-4.
We recorded cortical-evoked responses with a whole-scalp neuromagnetometer to study human brain dynamics associated with audiotactile interaction. The subjects received unilateral auditory (A) or tactile (T) stimuli, or both stimuli simultaneously (AT), alternating to the left and right side. Responses to AT stimuli differed significantly from the algebraic sum of responses to A and T stimuli (A + T) at 75-85 and 105-130 ms and indicated suppressive audiotactile interaction. Source modeling revealed that the earlier interaction occurred in the contralateral posterior parietal cortex and the later interaction in the contralateral parietal opercula between the SII cortex and the auditory cortex. The interaction was significantly stronger in the left than the right hemisphere. In most subjects, AT responses were far more similar to T than to A responses, suggesting suppression of auditory processing during the spatially and temporally concordant audiotactile stimuli in which the tactile component was subjectively more salient.
我们使用全头皮神经磁强计记录皮层诱发反应，以研究与听觉触觉相互作用相关的人类脑动力学。受试者接受单侧听觉（A）或触觉（T）刺激，或同时接受两种刺激（AT），左右两侧交替进行。在75 - 85毫秒和105 - 130毫秒时，对AT刺激的反应与对A和T刺激的代数和（A + T）有显著差异，表明存在抑制性听觉触觉相互作用。源模型显示，早期相互作用发生在对侧后顶叶皮层，后期相互作用发生在SII皮层和听觉皮层之间的对侧顶叶岛盖。左侧半球的相互作用明显强于右侧半球。在大多数受试者中，AT反应与T反应远比与A反应相似，这表明在空间和时间上一致的听觉触觉刺激中，当触觉成分在主观上更突出时，听觉处理受到抑制。
