Proestakis G, Bratthall G, Söderholm G, Kullendorff B, Gröndahl K, Rohlin M, Attström R
Department of Periodontology, Faculty of Odontology, University of Lund, Sweden.
J Clin Periodontol. 1992 Nov;19(10):766-73. doi: 10.1111/j.1600-051x.1992.tb02168.x.
The present study evaluated clinically and radiographically the short-term results of the healing of infrabony defects at maxillary premolars treated according to guided tissue regeneration (GTR). 9 patients with bilateral presence of infrabony defects with or without furcation involvements at maxillary premolars were selected. At baseline assessments of plaque and gingival indices, bleeding, probing pocket depth and attachment level, and furcation measurements were recorded. Conventional radiographs were obtained in a way that assured a reproducible projection geometry. One premolar was randomly treated with GTR and the contralateral with open debridement. Clinical and radiographic examinations were performed again 6 months postoperatively. The bone tissue changes were assessed by means of conventional radiographs and subtraction images. Sites treated by both procedures demonstrated an improvement of gingival conditions and a reduction of pocket depths. A statistically significant attachment gain was obtained for the test (mean 1.2 mm), but not for the control sites (mean 0.6 mm). The differences, though, were not significant between the test and control sites. Limited improvement in furcation closure was recorded. The radiographic examination demonstrated loss of bone tissue in four sites treated with GTR. The findings suggest that the regeneration of the periodontal soft and bone tissues was not significantly enhanced with the GTR therapy.
本研究从临床和影像学方面评估了根据引导组织再生术（GTR）治疗的上颌前磨牙骨下袋缺损愈合的短期效果。选择了9例上颌前磨牙双侧存在骨下袋缺损伴或不伴根分叉病变的患者。在基线时评估菌斑和牙龈指数、出血情况、探诊袋深度和附着水平，并记录根分叉测量值。以确保投影几何形状可重复的方式获取传统X线片。随机选择一颗前磨牙采用GTR治疗，对侧采用开放清创术治疗。术后6个月再次进行临床和影像学检查。通过传统X线片和减影图像评估骨组织变化。两种治疗方法治疗的部位均显示牙龈状况改善，袋深度减小。试验组获得了统计学上显著的附着增加（平均1.2mm），而对照组未获得（平均0.6mm）。然而，试验组和对照组之间的差异并不显著。记录到根分叉闭合的改善有限。影像学检查显示，4个采用GTR治疗的部位出现了骨组织丧失。研究结果表明，GTR治疗并未显著促进牙周软组织和骨组织的再生。
