贫血和肝脾肿大作为一名患有佝偻病和继发性骨髓纤维化儿童的首发症状。
Anemia and hepatosplenomegaly as presenting features in a child with rickets and secondary myelofibrosis.
作者信息
Gruner Barbara A, DeNapoli Thomas S, Elshihabi Said, Britton Howard A, Langevin Anne-Marie, Thomas Paul J, Weitman Steven D
机构信息
Department of Pediatrics, University of Texas Health Science Center, San Antonio, Texas, USA.
出版信息
J Pediatr Hematol Oncol. 2003 Oct;25(10):813-5. doi: 10.1097/00043426-200310000-00015.
Anemia and hepatosplenomegaly are common reasons for referring a child to a pediatric hematologist or oncologist. Among the many causes for these findings is severe rickets, which has been shown to be associated with secondary myelofibrosis and myeloid metaplasia. The authors present the case of an infant with severe rickets and secondary myelofibrosis and review the differential diagnosis of hepatosplenomegaly from the viewpoint of the pediatric hematologist/oncologist.
贫血和肝脾肿大是儿童被转诊至儿科血液科医生或肿瘤科医生处的常见原因。这些表现的众多病因中包括严重佝偻病，已证实其与继发性骨髓纤维化和髓外化生有关。作者介绍了一名患有严重佝偻病和继发性骨髓纤维化的婴儿病例，并从儿科血液科医生/肿瘤科医生的角度回顾了肝脾肿大的鉴别诊断。
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