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关于在高剂量率近距离放射治疗中使用C型臂荧光透视进行治疗计划

On the use of C-arm fluoroscopy for treatment planning in high dose rate brachytherapy.

作者信息

Liu Lizhong, Bassano Daniel A, Prasad Satish C, Keshler Bonnie L, Hahn Seung S

机构信息

Department of Radiation Oncology, SUNY Upstate Medical University, Syracuse, New York 13210, USA.

出版信息

Med Phys. 2003 Sep;30(9):2297-302. doi: 10.1118/1.1598851.

Abstract

Treatment planning for brachytherapy requires the acquisition of geometrical information of the implant applicator and the patient anatomy. This is typically done using a simulator or a computed tomography scanner. In this study, we present a different method by which orthogonal images from a C-arm fluoroscopic machine is used for high dose rate brachytherapy treatment planning. A typical C-arm is not isocentric, and it does not have the mechanical accuracy of a simulator. One solution is to place a reconstruction box with fiducial markers around the patient. However, with the limited clearance of the C-arm this method is very cumbersome to use, and is not suitable for all patients and implant sites. A different approach is adopted in our study. First, the C-arm movements are limited to three directions only between the two orthogonal images: the C-orbital rotation, the vertical column, and the horizontal arm directions. The amounts of the two linear movements and the geometric parameters of the C-arm orbit are used to calculate the location of the crossing point of the two beams and thus the magnification factors of the two images. Second, the fluoroscopic images from the C-arm workstation are transferred in DICOM format to the planning computer through a local area network. Distortions in the fluoroscopic images, with its major component the "pincushion" effect, are numerically removed using a software program developed in house, which employs a seven-parameter polynomial filter. The overall reconstruction accuracy using this method is found to be 2 mm. This filmless process reduces the overall time needed for treatment planning, and greatly improves the workflow for high dose rate brachytherapy procedures. Since its commissioning nearly three years ago, this system has been used extensively at our institution for endobronchial, intracavitary, and interstitial brachytherapy planning with satisfactory results.

摘要

近距离放射治疗的治疗计划需要获取植入施源器和患者解剖结构的几何信息。这通常使用模拟定位机或计算机断层扫描仪来完成。在本研究中,我们提出了一种不同的方法,即使用C形臂荧光透视机的正交图像进行高剂量率近距离放射治疗的治疗计划。典型的C形臂不是等中心的,并且不具备模拟定位机的机械精度。一种解决方案是在患者周围放置一个带有基准标记的重建盒。然而,由于C形臂的间隙有限,这种方法使用起来非常麻烦,并且不适用于所有患者和植入部位。我们的研究采用了一种不同的方法。首先,C形臂的移动仅限于在两个正交图像之间的三个方向:C形臂轨道旋转、垂直立柱和水平臂方向。利用两个线性移动的量和C形臂轨道的几何参数来计算两束射线交叉点的位置,从而计算出两个图像的放大倍数。其次,来自C形臂工作站的荧光透视图像通过局域网以DICOM格式传输到计划计算机。使用内部开发的软件程序,通过七参数多项式滤波器对荧光透视图像中的畸变(其主要成分是“枕形”效应)进行数字消除。使用该方法的整体重建精度为2毫米。这种无胶片流程减少了治疗计划所需的总时间,并大大改善了高剂量率近距离放射治疗程序的工作流程。自近三年前投入使用以来,该系统已在我们机构广泛用于支气管内、腔内和组织间近距离放射治疗计划,效果令人满意。

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