Rojas E Leticia, Al-Dweri Feras M O, Lallena Antonio M, Bodineau Coral, Galán Pedro
Departamento de Física Moderna, Universidad de Granada, E-18071 Granada, Spain.
Med Phys. 2003 Sep;30(9):2482-92. doi: 10.1118/1.1599653.
The dosimetry for radiocolloid therapy of cystic craniopharyngiomas is investigated. Analytical calculations based on the Loevinger and the Berger formulas for electrons and photons, respectively, are compared with Monte Carlo simulations. The role of the material of which the colloid introduced inside the craniopharyngioma is made of as well as that forming the cyst wall is analyzed. It is found that the analytical approaches provide a very good description of the simulated data in the conditions where they can be applied (i.e., in the case of a uniform and infinite homogeneous medium). However, the consideration of the different materials and interfaces produces a strong reduction of the dose delivered to the cyst wall in relation to that predicted by the Loevinger and the Berger formulas.
对囊性颅咽管瘤放射性胶体治疗的剂量测定进行了研究。分别基于Loevinger公式和Berger公式对电子和光子进行的分析计算与蒙特卡罗模拟进行了比较。分析了颅咽管瘤内引入的胶体以及构成囊肿壁的材料的作用。结果发现，分析方法在其适用的条件下（即在均匀且无限均匀介质的情况下）能够很好地描述模拟数据。然而，考虑不同的材料和界面会使传递到囊肿壁的剂量相对于Loevinger公式和Berger公式预测的剂量大幅降低。
