Urmey William F
Department of Anesthesiology, Hospital for Special Surgery, Weill Medical College of Cornell University, 535 East 70th Street, New York, NY 100021, USA.
Best Pract Res Clin Anaesthesiol. 2003 Sep;17(3):335-46. doi: 10.1016/s1521-6896(03)00015-6.
Spinal anaesthesia in the outpatient is characterized by rapid onset and offset, easy administration, minimal expense, and minimal side effects or complications. Spinal anaesthesia offers advantages for outpatient lower extremity, perineal, and many abdominal and gynaecological procedures. Development of small-gauge, pencil-point needles are responsible for the success of outpatient spinal anaesthesia with acceptable rates (0-2%) of postdural puncture headache (PDPH). Compared with peripheral nerve blocks, spinal anaesthesia has a more predictable offset. There are many possible choices of local anaesthetics for outpatient spinal anaesthesia. These include lidocaine, prilocaine, mepivacaine and small doses of bupivacaine. Meperidine has local anaesthetic properties in addition to its opiate properties. It has been used as the sole intrathecal agent for spinal anaesthesia but has no real advantages over lidocaine. Mepivacaine and lidocaine have each been associated with transient neurological symptoms (TNS) following intrathecal administration. This has stimulated development of alternative agents, including combinations of local anaesthetics and opioids. Lidocaine remains the most useful agent for outpatient spinal anaesthesia. For longer procedures, mepivacaine is an excellent spinal anaesthetic agent. Attention to technique, reduction of dose and addition of fentanyl to lidocaine result in effective spinal anaesthesia with rapid recovery and a low incidence of significant side effects or complications.
门诊患者的脊髓麻醉具有起效快、消退快、给药方便、费用低廉以及副作用或并发症极少的特点。脊髓麻醉对于门诊患者的下肢、会阴以及许多腹部和妇科手术具有优势。小口径铅笔头针的研制促成了门诊脊髓麻醉的成功,其硬膜穿刺后头痛(PDPH)发生率可接受(0 - 2%)。与外周神经阻滞相比,脊髓麻醉的消退更可预测。门诊脊髓麻醉有多种局部麻醉药可供选择。这些包括利多卡因、丙胺卡因、甲哌卡因和小剂量布比卡因。哌替啶除具有阿片类特性外还具有局部麻醉特性。它曾被用作脊髓麻醉的唯一鞘内用药,但与利多卡因相比并无实际优势。甲哌卡因和利多卡因鞘内给药后均与短暂性神经症状(TNS)有关。这促使了包括局部麻醉药与阿片类药物联合使用在内的替代药物的研发。利多卡因仍是门诊脊髓麻醉最有用的药物。对于较长时间的手术,甲哌卡因是一种出色的脊髓麻醉药。注重技术、减少剂量以及在利多卡因中添加芬太尼可产生有效的脊髓麻醉,恢复迅速且严重副作用或并发症发生率低。