Stevenson A C, Araya-Kleinsteuber B, Sethi R S, Mehta H M, Lowe C R
Institute of Biotechnology, University of Cambridge, Tennis Court Road, Cambridge, UK CB2 1QT.
Analyst. 2003 Sep;128(9):1175-80. doi: 10.1039/b305257e.
A planar spiral coil has been used to induce hypersonic evanescent waves in a quartz substrate with the unique ability to focus the acoustic wave down onto the chemical recognition layer. These special sensing conditions were achieved by investigating the application of a radio frequency current to a coaxial waveguide and spiral coil, so that wideband repeating electrical resonance conditions could be established over the MHz to GHz frequency range. At a selected operating frequency of 1.09 GHz, the evanescent wave depth of a quartz crystal hypersonic resonance is reduced to 17 nm, minimising unwanted coupling to the bulk fluid. Verification of the validity of the hypersonic resonance was carried out by characterising the system electrically and acoustically: Impedance calculations of the combined coil and coaxial waveguide demonstrated an excellent fit to the measured data, although above 400 MHz a transition zone was identified where unwanted impedance is parasitic of the coil influence efficiency, so the signal-to-noise ratio is reduced from 3000 to 300. Acoustic quartz crystal resonances at intervals of precisely 13.2138 MHz spacing, from the 6.6 MHz ultrasonic range and onto the desired hypersonic range above 1 GHz, were incrementally detected. Q factor measurements demonstrated that reductions in energy lost from the resonator to the fluid interface were consistent with the anticipated shrinkage of the evanescent wave with increasing operating frequency. Amplitude and frequency reduction in contact with a glucose solution was demonstrated at 1.09 GHz. The complex physical conditions arising at the solid-liquid interface under hypersonic entrainment are discussed with respect to acceleration induced slippage, rupture, longitudinal and shear radiation and multiphase relaxation affects.
平面螺旋线圈已被用于在石英基板中感应高超声速倏逝波,该线圈具有将声波聚焦到化学识别层上的独特能力。通过研究向同轴波导和螺旋线圈施加射频电流来实现这些特殊的传感条件,从而可以在兆赫兹到吉赫兹频率范围内建立宽带重复电共振条件。在选定的1.09 GHz工作频率下,石英晶体高超声速共振的倏逝波深度减小到17 nm,从而将与主体流体的不必要耦合降至最低。通过对系统进行电学和声学表征来验证高超声速共振的有效性:组合线圈和同轴波导的阻抗计算结果与测量数据非常吻合,尽管在400 MHz以上识别出一个过渡区,在该区域中,不需要的阻抗是线圈影响效率的寄生因素,因此信噪比从3000降低到300。精确间隔13.2138 MHz,从6.6 MHz超声范围到1 GHz以上的所需高超声速范围,逐步检测到声学石英晶体共振。品质因数测量表明,随着工作频率的增加,谐振器向流体界面损失的能量减少与预期的倏逝波收缩一致。在1.09 GHz下证明了与葡萄糖溶液接触时的幅度和频率降低。讨论了在高超声速夹带作用下固液界面出现的复杂物理条件,涉及加速引起的滑移、破裂、纵向和剪切辐射以及多相弛豫影响。