[The effects of age and sex on the acute toxicity of two barbiturate anesthetics in rats].
作者信息
Bruguerolle B, Mesdjian E, Valli M, Blanc M C, Jadot G, Bouyard P
出版信息
C R Seances Soc Biol Fil. 1977;171(4):846-9.
PMID:145291
Abstract
The study of the acute toxicity of two barbiturics anaesthetics (pentobarbital and thiopental) shows the newborn period a higher susceptibility of the young rat, probably due to an immaturity of biotransformations enzymatic systems or to an increased blood-brain-barrier permeability.
摘要
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