从开菲尔中分离出的不同乳酸杆菌属菌株的抗菌特性。

The antimicrobial properties of different strains of Lactobacillus spp. isolated from kefir.

作者信息

Santos A, San Mauro M, Sanchez A, Torres J M, Marquina D

机构信息

Department of Microbiology III, Biology Faculty, Complutense University of Madrid, Spain.

出版信息

Syst Appl Microbiol. 2003 Sep;26(3):434-7. doi: 10.1078/072320203322497464.

DOI:10.1078/072320203322497464

PMID:14529186

Abstract

The characteristics of 58 strains of Lactobacillus spp. isolated from kefir were studied. These strains were tested for adherence to human enterocyte-like Caco-2 cells, resistance to acidic pH and bile acid, antimicrobial activities against enteropathogenic bacteria and inhibition of Salmonella typhimurium attachment to Caco-2 cells. The best probiotic properties were observed in L. acidophilus CYC 10051 and L. kefiranofaciens CYC 10058. L. kefiranofaciens CYC 10058 produced an exopolysaccharide, which revealed that it was closely related to kefiran, a polysaccharide with antitumoral properties. This is the first in vitro study about the antimicrobial characteristics of the Lactobacillus population of kefir.

摘要

对从开菲尔中分离出的58株乳杆菌属菌株的特性进行了研究。对这些菌株进行了检测，包括对人肠上皮样Caco-2细胞的黏附性、对酸性pH值和胆汁酸的抗性、对肠道病原菌的抗菌活性以及对鼠伤寒沙门氏菌黏附Caco-2细胞的抑制作用。在嗜酸乳杆菌CYC 10051和开菲尔糖乳杆菌CYC 10058中观察到了最佳的益生菌特性。开菲尔糖乳杆菌CYC 10058产生了一种胞外多糖，这表明它与具有抗肿瘤特性的多糖开菲尔多糖密切相关。这是关于开菲尔乳杆菌群体抗菌特性的首次体外研究。