Dietz H P, Vancaillie P, Svehla M, Walsh W, Steensma A B, Vancaillie T G
Royal Hospital for Women, New South Wales, Australia.
Int Urogynecol J Pelvic Floor Dysfunct. 2003 Oct;14(4):239-43; discussion 243. doi: 10.1007/s00192-003-1041-8. Epub 2003 Aug 5.
Synthetic suburethral slings have recently become popular despite the risk of erosion commonly associated with synthetic implants. Some of these materials seem to have unexpectedly low erosion rates. Based on the hypothesis that erosion is due, in part, to biomechanical properties, we undertook an in vitro study. The biomechanical properties of eight non-resorbable synthetic implant materials, stiffness (slope, N/mm) and peak load (N) were determined from load vs. displacement curves. Open-weave Prolene mesh showed unique biomechanical properties compared to other tested materials. The tension- free vaginal tape had the lowest initial stiffness (0.23 N/mm), i.e. low resistance to deformation at forces below the elastic limit, whereas the stiffest implant tested, a nylon tape, reached 6.83 N/mm. We concluded that the TVT and other wide-weave Prolene tapes have unique biomechanical characteristics. These properties may be at least partly responsible for the apparent clinical success of the implants.
尽管合成尿道悬吊带存在与合成植入物相关的侵蚀风险，但最近它已变得很流行。其中一些材料的侵蚀率似乎出人意料地低。基于侵蚀部分归因于生物力学特性这一假设，我们进行了一项体外研究。从载荷与位移曲线确定了八种不可吸收合成植入材料的生物力学特性，即刚度（斜率，N/mm）和峰值载荷（N）。与其他测试材料相比，开放式编织的普理灵网片显示出独特的生物力学特性。无张力阴道吊带的初始刚度最低（0.23 N/mm），即在低于弹性极限的力作用下对变形的抵抗力较低，而测试的最硬植入物——尼龙带，刚度达到6.83 N/mm。我们得出结论，经阴道无张力尿道中段吊带术（TVT）和其他宽编织普理灵带具有独特的生物力学特征。这些特性可能至少部分是植入物在临床上明显成功的原因。
