Courrière P, Paubel J P, Nivière P
C R Seances Soc Biol Fil. 1977;171(4):979-82.
In this study, the authors propose a comparison between conformational properties and pharmacological activity of a series of adrenergic phenethylamines; in particular they conclude that if the alpha adrenergic compounds adopt a gauche conformation, beta adrenergics prefer a trans form.
在本研究中,作者提出了一系列肾上腺素能苯乙胺的构象性质与药理活性之间的比较;特别是他们得出结论,如果α肾上腺素能化合物采用 gauche 构象,β肾上腺素能化合物则更喜欢反式构象。