Tilles Stephen A
Northwest Asthma and Allergy, Seattle, WA 98105, USA.
Curr Allergy Asthma Rep. 2003 Nov;3(6):467-72. doi: 10.1007/s11882-003-0056-z.
Vocal cord dysfunction (VCD) is a nonorganic disorder of the larynx that involves unintentional paradoxical adduction of the vocal cords while breathing. The resultant symptoms can include dyspnea, chest tightness, cough, throat tightness, wheezing, or voice change. Most patients with VCD are female, and among adolescents and children, VCD tends to be triggered by exercise and is typically confused with exercise-induced asthma. Both gastroesophageal reflux disease (GERD) and psychiatric illness have been reported as having strong associations with VCD, although, to date, there is no evidence that either causes VCD. VCD often coexists with asthma, and should be suspected in any patient in whom asthma treatment fails. Confirming the diagnosis involves direct visualization of abnormal vocal cord motion, and this usually only occurs during symptoms. Adolescent athletes often require free running exercise challenge to reproduce their symptoms and confirm abnormal vocal cord motion laryngoscopically. The primary treatment for VCD involves a combination of patient education and speech therapy, and, in most cases, patients may resume their activities without significant limitation.
声带功能障碍(VCD)是一种喉部的非器质性疾病,表现为呼吸时声带意外地反常内收。由此产生的症状可能包括呼吸困难、胸闷、咳嗽、喉咙发紧、喘息或声音改变。大多数VCD患者为女性,在青少年和儿童中,VCD往往由运动诱发,通常会与运动诱发的哮喘相混淆。尽管迄今为止尚无证据表明胃食管反流病(GERD)和精神疾病会导致VCD,但它们都被报道与VCD有密切关联。VCD常与哮喘并存,对于任何哮喘治疗无效的患者都应怀疑患有VCD。确诊需要直接观察声带的异常运动,而这通常只在症状发作时出现。青少年运动员通常需要进行自由跑步运动激发试验以重现症状,并通过喉镜检查确认声带运动异常。VCD的主要治疗方法包括患者教育和言语治疗,在大多数情况下,患者可以不受显著限制地恢复活动。