Kamiyama R, Shimokawa R
Bull Tokyo Med Dent Univ. 1977 Dec;24(4):239-47.
The enzyme activity for alpha-naphthyl-acetate esterase, naphthol-AS-acetate esterase, naphthol-AS-D-chloroacetate esterase, acid phosphatase, L(+)-tartrate-resistant acid phosphatase, adenosine triphosphatase, and 5'-nucleotidase was examined on the neoplastic cells of giant follicular lymphoblastoma, the so-called reticulum cell sarcoma and Sézary syndrome. The neoplastic cells of giant follicular lymphoblastoma showed distinct activity for adenosine triphosphatase and 5'-nucleotidase, and those of the so-called reticulum cell sarcoma had no characteristic nature of the reticulum cells or histiocytes enzyme histochemically. These findings suggest that these neoplastic cells may be derived from the B-cell system. In Sézary syndrome, acid phosphatase activity was localized in a small paranuclear area in Sézary cells, which were considered to have a T-cell nature. It is thought that these enzyme histochemical methods are easy and useful in differentiating the B- or T-cell nature and the classification of non-Hodgkin's lymphomas.
检测了α-萘乙酸酯酶、萘酚-AS-乙酸酯酶、萘酚-AS-D-氯乙酸酯酶、酸性磷酸酶、L(+)-酒石酸抗性酸性磷酸酶、三磷酸腺苷酶和5'-核苷酸酶在巨大滤泡性淋巴瘤、所谓的网状细胞肉瘤和Sezary综合征的肿瘤细胞中的酶活性。巨大滤泡性淋巴瘤的肿瘤细胞对三磷酸腺苷酶和5'-核苷酸酶表现出明显活性，而所谓网状细胞肉瘤的肿瘤细胞在酶组织化学上没有网状细胞或组织细胞的特征性性质。这些发现表明这些肿瘤细胞可能来源于B细胞系统。在Sezary综合征中，酸性磷酸酶活性定位于Sezary细胞中的一个小核旁区域，这些细胞被认为具有T细胞性质。据认为，这些酶组织化学方法在区分B或T细胞性质以及非霍奇金淋巴瘤的分类方面简便且有用。
