Kim Myung-Hwan, Lee Sang Soo
Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Songpa-gu, Seoul, Korea.
Korean J Gastroenterol. 2003 Aug;42(2):89-95.
Hepatolithiasis, or primary intrahepatic stones, is prevalent in the Far East. The majority of primary intrahepatic stones were calcium bilirubinate stones 30-40 years ago in Korea. However, intrahepatic stones with high cholesterol purity have recently been recognized. Since 1990s, mixed stones constituting about 40-50% of all intrahepatic stones, and pure intrahepatic cholesterol stones have been observed in Korea. Although advances in interventional radiological techniques, cholangioscopic technique, and novel surgical technique have led to significant changes in treating the patients with hepatolithiasis, it is still considered as an intractable disease and more common in Korea than western countries. Therefore, Korean gastroenterologists should have more interest and accomplish passionate researches on hepatolithiasis.
肝内胆管结石,即原发性肝内结石,在远东地区较为常见。30至40年前,韩国大多数原发性肝内结石为胆红素钙结石。然而,近年来已发现胆固醇纯度较高的肝内结石。自20世纪90年代以来,韩国已观察到占所有肝内结石约40%-50%的混合性结石以及纯肝内胆固醇结石。尽管介入放射技术、胆道镜技术和新型手术技术的进步已使肝内胆管结石患者的治疗发生了重大变化,但该病仍被视为一种难治性疾病,在韩国比西方国家更为常见。因此,韩国胃肠病学家应更加关注并积极开展关于肝内胆管结石的研究。