Oddi 括约肌松弛：胆石病的一个重要因素。
Sphincter of Oddi laxity: an important factor in hepatolithiasis.
机构信息
Department of Hepatobiliary and Pancreatic Surgery, Key Laboratory of Multi-Organ Transplantation of Ministry of Public Health, Key Laboratory of Organ Transplantation of Zhejiang Province, the First Affiliated Hospital, School of Medicine, Zhejiang University, 79 Qingchun Road, Hangzhou 310003, Zhejiang Province, China.
出版信息
World J Gastroenterol. 2010 Feb 28;16(8):1014-8. doi: 10.3748/wjg.v16.i8.1014.
AIM
To evaluate the importance of sphincter of Oddi laxity (SOL) in hepatolithiasis (HL).
METHODS
Subjects included 98 patients diagnosed with HL between 2002 and 2007. Detailed histories were taken and the subjects were monitored until July 2008. HL patients were divided into two groups: Group I included 45 patients with SOL, and Group II included 53 patients without. Recurrence and reoperation indices of both groups were calculated and compared.
RESULTS
The recurrence index was 0.135 in Group I and 0.018 in Group II (P < 0.001). The reoperation index was 0.070 in Group I and 0.010 in Group II (P < 0.001). The mean frequency of biliary operation was 2.07 in Group I and 1.21 in Group II (P = 0.001). Differences between the two groups are significant.
CONCLUSION
HL patients with SOL tend to have a higher risk of recurrence and a larger demand for reoperation than those without this condition.
目的
评估 Oddi 括约肌松弛（SOL）在胆石病（HL）中的重要性。
方法
纳入 2002 年至 2007 年间确诊为 HL 的 98 例患者。详细询问病史，并对患者进行监测，直至 2008 年 7 月。将 HL 患者分为两组：I 组 45 例存在 SOL，II 组 53 例不存在 SOL。比较两组患者的复发和再手术指数。
结果
I 组的复发指数为 0.135，II 组为 0.018（P < 0.001）。I 组的再手术指数为 0.070，II 组为 0.010（P < 0.001）。I 组的胆道手术平均频率为 2.07 次，II 组为 1.21 次（P = 0.001）。两组之间存在显著差异。
结论
与无 SOL 的 HL 患者相比，存在 SOL 的 HL 患者复发风险更高，再手术需求更大。
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