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本地儿童组主动脉缩窄球囊血管成形术:急性结果及中期血管造影再评估

Balloon angioplasty of native coarctation of the aorta in a local group of children: acute results and midterm angiographic re-assessment.

作者信息

Brown S C, Bruwer A D

机构信息

Paediatric Cardiology, Department of Paediatrics and Child Health-G69, University of the Free State, Bloemfontein, South Africa.

出版信息

Cardiovasc J S Afr. 2003 Jul-Aug;14(4):177-81.

Abstract

OBJECTIVE

Balloon angioplasty of native coarctation of the aorta is gaining acceptance as an alternative to surgery in children. The aim of this study was to assess the acute and midterm effectiveness and safety of the procedure.

METHODS

During a 3-year period, nine patients with native coarctation underwent balloon angioplasty at a median age of 2.9 years (range: 4 mo - 12 y) and median weight of 11 kg (range: 3.1 - 51 kg). Balloon diameter selected was at least twice the diameter of the narrowed segment, but never more than the diameter of the aorta at diaphragmatic level.

RESULTS

There was a significant improvement in the mean systolic gradient across the coarctation from 36 +/- 13mm Hg to 4 +/- 4 mm Hg (p < 0.001), and in the mean diameter of the narrowed segment from 4 +/- 1.3 mm to 7.2 +/- 2.7 mm (p < 0.001). There was no immediate mortality or complication. Follow-up catheterisation was done in eight patients, a mean of 2.7 years (range: 0.8 - 4 y) after the initial procedure. No evidence of restenosis was found, but one patient developed an aneurysm that was surgically resected.

CONCLUSION

Balloon angioplasty is effective and safe for the treatment of native coarctation in children. Radiographic follow-up is advisable in the midterm. Balloon angioplasty offers an alternative to surgery in the treatment of selected children older than 3 months with native coarctation of the aorta.

摘要

目的

对于儿童主动脉缩窄,球囊血管成形术作为手术替代方案正逐渐被接受。本研究旨在评估该手术的急性及中期有效性和安全性。

方法

在3年期间,9例原发性主动脉缩窄患者接受了球囊血管成形术,中位年龄为2.9岁(范围:4个月至12岁),中位体重为11千克(范围:3.1至51千克)。所选球囊直径至少是狭窄段直径的两倍,但绝不超过膈肌水平主动脉的直径。

结果

缩窄部位的平均收缩压梯度从36±13毫米汞柱显著改善至4±4毫米汞柱(p<0.001),狭窄段的平均直径从4±1.3毫米增至7.2±2.7毫米(p<0.001)。无即刻死亡或并发症发生。8例患者进行了随访导管检查,初次手术后平均2.7年(范围:0.8至4年)。未发现再狭窄证据,但有1例患者出现动脉瘤并接受了手术切除。

结论

球囊血管成形术治疗儿童原发性主动脉缩窄有效且安全。中期建议进行影像学随访。对于3个月以上患有原发性主动脉缩窄的特定儿童,球囊血管成形术为手术提供了一种替代方案。

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