Bux J, Westphal E, de Sousa F, Mueller-Eckhardt G, Mueller-Eckhardt C
Institute for Clinical Immunology and Transfusion Medicine, University of Giessen, FRG.
J Reprod Immunol. 1992 Oct;22(3):299-302. doi: 10.1016/0165-0378(92)90050-e.
Alloimmunization of a mother against granulocytes causing alloimmune neonatal neutropenia (ANN) in her newborn was found likely to be attributed to previous intradermal injections of paternal lymphocytes. Immunotherapy with leukocytes which was performed for recurrent spontaneous abortions hence provides the possibility of granulocyte alloimmunization and increases the risk of the occurrence of ANN.