Gawenda Michael, Zaehringer Markus, Brunkwall Jan
Division of Vascular Surgery, Medical Centre, University of Cologne, Germany.
J Endovasc Ther. 2003 Aug;10(4):745-51. doi: 10.1177/152660280301000410.
To compare the outcomes of open versus endovascular repair of para-anastomotic aneurysms (PAA) in the aortic and iliac arteries in a cohort of patients who fulfilled morphological criteria for endovascular repair.
A retrospective review of 31 consecutive patients with PAA treated between 1985 and 2002 identified 26 (84%) patients who would have been candidates for endovascular repair based on preoperative computed tomography and angiography. Of these 26 patients, 10 (9 men; median age 65 years, range 60-75) underwent endovascular repair; the remaining 16 patients (14 men; median age 61.5 years, range 49-78) had open repair. The baseline data and outcome measures were compared between the treatment groups.
The patient groups were well matched for age, sex, weight, risk factors, comorbidities, aneurysm length, and elapsed time from initial graft placement. Both groups had technically successful PAA repairs; however, median blood loss (300 versus 1000 mL; p=0.05) and procedural time (100 versus 215 minutes; p<0.001) were significantly reduced in the endovascular group. Median transfusion volume was significantly greater (1000 versus 0 mL; p=0.01) in the surgically treated patients. The median stay in ICU was similar (18 versus 24 hours in the surgical cohort). Length of stay was significantly shorter in the endovascular group: 7.5 versus 17.0 days (p=0.001) after the repair and 11 versus 22 days (p=0.01) for overall hospitalization. One (10%) patient in the endovascular group died from a myocardial infarction on the third postoperative day. In the open group, there were 3 (19%) procedure-related deaths.
Patients with PAA who were endograft candidates but who were treated with open repair experienced more morbidity and had more complications than patients treated with stent-grafts. If long-term follow-up demonstrates durable results, stent-graft repair may become the therapy of choice in PAAs.
在一组符合血管腔内修复形态学标准的患者中,比较主动脉和髂动脉吻合口旁动脉瘤(PAA)开放修复与血管腔内修复的效果。
对1985年至2002年间连续治疗的31例PAA患者进行回顾性研究,根据术前计算机断层扫描和血管造影,确定26例(84%)患者适合血管腔内修复。在这26例患者中,10例(9例男性;中位年龄65岁,范围60 - 75岁)接受了血管腔内修复;其余16例患者(14例男性;中位年龄61.5岁,范围49 - 78岁)接受了开放修复。比较治疗组之间的基线数据和结果指标。
患者组在年龄、性别、体重、危险因素、合并症、动脉瘤长度以及初次植入移植物后的时间方面匹配良好。两组PAA修复在技术上均成功;然而,血管腔内修复组的中位失血量(300 vs 1000 mL;p = 0.05)和手术时间(100 vs 215分钟;p < 0.001)显著减少。手术治疗患者的中位输血量显著更多(1000 vs 0 mL;p = 0.01)。重症监护病房(ICU)的中位住院时间相似(手术组为18 vs 24小时)。血管腔内修复组的住院时间显著更短:修复后为7.5 vs 17.0天(p = 0.001),总体住院时间为11 vs 22天(p = 0.01)。血管腔内修复组有1例(10%)患者在术后第三天死于心肌梗死。开放组有3例(19%)与手术相关的死亡。
适合接受血管腔内修复但接受开放修复的PAA患者比接受支架移植物治疗的患者有更多的发病率和并发症。如果长期随访显示结果持久,支架移植物修复可能成为PAA的首选治疗方法。