Ortega S, Muros M A, Llamas J M, Ramos C, Sabatel G, López J M, Ramírez A, Arenas R
Servicio de Medicina Nuclear, Hospital Universitario Virgen de las Nieves, Granada.
Rev Esp Med Nucl. 2003 Sep-Oct;22(5):336-9. doi: 10.1016/s0212-6982(03)72210-1.
Clear cell sarcoma of the soft parts (CCSSP) is a rare and highly malignant tumor. This is a case report of a 31 years old woman who presented with a tumor in the internal face of left thigh. The tumor biopsy was suggestive of a possible malignant tumor of the peripheral nerve sheath (malignant schwannoma). Biochemical analyses, computed tomography and magnetic resonance were performed and reported a sarcoma of soft parts (CCSSP) without abnormal inguinal lymph nodes. With this diagnostic suspicion, the patient was sent to the Nuclear Medicine Service of our center where a 201Thallium scintigraphy study was performed. In this study, it showed the primary tumor together with a hot spot in the homolateral inguinal region, suggestive of the presence of a metastastic lymph node. This finding would change the surgical attitude in the patient, including inguinal lymphadenectomy. The post-surgical histological study confirmed a clear cell sarcoma of soft parts (CCSSP) with a metastatic inguinal lymph node.
软组织透明细胞肉瘤(CCSSP)是一种罕见的高度恶性肿瘤。本文报告一例31岁女性患者,其左大腿内侧面出现肿瘤。肿瘤活检提示可能为周围神经鞘恶性肿瘤(恶性神经鞘瘤)。进行了生化分析、计算机断层扫描和磁共振成像检查,结果报告为无腹股沟淋巴结异常的软组织肉瘤(CCSSP)。基于这一诊断怀疑,患者被转至本中心核医学科,进行了铊-201闪烁扫描检查。在这项检查中,显示出原发肿瘤以及同侧腹股沟区的一个热点,提示存在转移性淋巴结。这一发现将改变对该患者的手术方案,包括进行腹股沟淋巴结清扫术。术后组织学研究证实为伴有腹股沟转移性淋巴结的软组织透明细胞肉瘤(CCSSP)。