Han Yun, Geng Hui, Feng Weibin, Tang Xiangjiang, Ou Aihua, Lao Yingrong, Xu Yinji, Lin Hao, Liu Hui, Li Yongwen
Guangdong Provincial TCM Hospital, Guangzhou 510120.
J Tradit Chin Med. 2003 Sep;23(3):214-7.
Sixty-nine patients with severe acute respiratory syndrome (SARS) discharged from Guangdong Provincial TCM Hospital were followed up from January to April 2003 during which the patients were asked to fill the questionnaire form and at the same time received blood routine examination, hepatic, renal, pulmonary and immune function tests, and spiral computerized tomography (CT) of the chest, color B-ultrasonography of the heart with the collected data treated by descriptive analysis and deductive analysis. The results showed that in the 69 followed-up patients, impairment of the hepatic function was found in 5 cases, hypoimmune state in 18, impediment of ventilation in the distal air passages with normal major air passages in 15, increased residual volume in 40, mild disturbance of pulmonary diffusion function in 14, incomplete absorption of inflammatory exudates, focal or multiple interstitial lesions, pulmonary interstitial fibrosis and pleural adhesion in 24; increased resistance or mild systolic hypertension in the pulmonary circulation, and segmental ischemia of the left myocardium in 34; and decreased visual acuity in 2. According to TCM differentiation 24 cases belonged to the type of deficiency of both qi and yin, 8 deficiency of both the heart and spleen, 37 depression of the liver and deficiency of the spleen, 18 intermingling with damp-heat, and 7 intermingling with stagnant blood. Some patients still had psychological problems. The study indicates that though clinically cured and discharged from hospital, some SARS patients have functional impairment of the heart, lung and liver, hypoimmune state as well as psychological problems, and need to be treated accordingly for a complete recovery. A rationale for suggested TCM treatment is expounded.
2003年1月至4月,对从广东省中医院出院的69例重症急性呼吸综合征(SARS)患者进行随访,期间让患者填写问卷调查表,同时进行血常规、肝肾功能、肺功能及免疫功能检查,胸部螺旋CT及心脏彩色B超检查,并对收集的数据进行描述性分析和归纳分析。结果显示,69例随访患者中,肝功能损害5例,免疫功能低下18例,大气道正常但小气道通气障碍15例,残气量增加40例,肺弥散功能轻度障碍14例,炎症渗出物吸收不全、局灶性或多发性间质病变、肺间质纤维化及胸膜粘连24例;肺循环阻力增加或轻度收缩期高血压,左心肌节段性缺血34例;视力下降2例。中医辨证:气阴两虚型24例,心脾两虚型8例,肝郁脾虚型37例,湿热夹杂型18例,瘀血夹杂型7例。部分患者仍存在心理问题。研究表明,部分SARS患者虽临床治愈出院,但存在心、肺、肝等功能损害、免疫功能低下及心理问题,需针对性治疗以促进全面康复,并阐述了中医治疗的理论依据。