Osadchuk L V, Shurkalova T A
Ontogenez. 1992 Jul-Aug;23(4):385-9.
The level of testosterone in serum and testes of the silver fox fetuses on days 31, 35, 40, 45, and 50 of gestation was determined using radioimmunoassay. In testes, testosterone was first detected at day 31; then its level gradually increased. Serum testosterone was detected only at day 40. Subsequent increase in its concentration was insignificant. Human chorionic gonadotropin stimulated testicular testosterone production in vitro beginning from day 40. We suggest that in the silver fox, testes are capable of responding to gonadotropins already by the day 40 of prenatal development but the formation of pituitary-gonadal axis proceeds until the end of embryogenesis.
采用放射免疫分析法测定了妊娠31、35、40、45和50天银狐胎儿血清和睾丸中的睾酮水平。在睾丸中，31天时首次检测到睾酮，随后其水平逐渐升高。血清睾酮仅在40天时被检测到，其浓度随后的升高并不显著。从40天开始，人绒毛膜促性腺激素在体外刺激睾丸睾酮的产生。我们认为，在银狐中，睾丸在产前发育的第40天就已经能够对促性腺激素作出反应，但垂体-性腺轴的形成一直持续到胚胎发育结束。
