阿尔茨海默病脑β/A4沉积物中补体蛋白和α1-抗糜蛋白酶的分布模式及功能状态 - Suppr

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超能文献

Distribution pattern and functional state of complement proteins and alpha 1-antichymotrypsin in cerebral beta/A4 deposits in Alzheimer's disease.

作者信息

Eikelenboom P, Hack C E, Kamphorst W, Rozemuller J M

机构信息

Dept of Psychiatry, Free University, Amsterdam.

出版信息

Res Immunol. 1992 Jul-Aug;143(6):617-20. doi: 10.1016/0923-2494(92)80044-l.

DOI:10.1016/0923-2494(92)80044-l

PMID:1455052

Abstract

摘要

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Distribution pattern and functional state of complement proteins and alpha 1-antichymotrypsin in cerebral beta/A4 deposits in Alzheimer's disease.阿尔茨海默病脑β/A4沉积物中补体蛋白和α1-抗糜蛋白酶的分布模式及功能状态

Res Immunol. 1992 Jul-Aug;143(6):617-20. doi: 10.1016/0923-2494(92)80044-l.

Expression of the Alzheimer amyloid-promoting factor antichymotrypsin is induced in human astrocytes by IL-1.白细胞介素-1可诱导人星形胶质细胞中阿尔茨海默病淀粉样蛋白促进因子抗胰凝乳蛋白酶的表达。

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Immunohistological study on the distribution of alpha 1-antichymotrypsin in Alzheimer's brain, compared to beta-amyloid precursor protein and beta-amyloid protein.与β-淀粉样前体蛋白和β-淀粉样蛋白相比，阿尔茨海默病大脑中α1-抗糜蛋白酶分布的免疫组织学研究。

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The protease inhibitor, alpha 1-antichymotrypsin, is a component of the brain amyloid deposits in normal aging and Alzheimer's disease.蛋白酶抑制剂α1-抗糜蛋白酶是正常衰老和阿尔茨海默病大脑淀粉样沉积物的一个组成部分。

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Alpha 1-antichymotrypsin in brain aging and disease.脑衰老和疾病中的α1-抗糜蛋白酶

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Amyloid P component and other acute-phase proteins associated with cerebellar A beta-deposits in Alzheimer's disease.淀粉样蛋白P成分及其他与阿尔茨海默病小脑β-淀粉样蛋白沉积相关的急性期蛋白。

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Alzheimer A beta neurotoxicity: promotion by antichymotrypsin, ApoE4; inhibition by A beta-related peptides.阿尔茨海默病β淀粉样蛋白神经毒性：抗胰凝乳蛋白酶、载脂蛋白E4的促进作用；β淀粉样蛋白相关肽的抑制作用。

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Alpha 1-antichymotrypsin is present together with the beta-protein in monkey brain amyloid deposits.α1-抗糜蛋白酶与β蛋白共同存在于猴脑淀粉样沉积物中。

Neuroscience. 1989;32(3):715-20. doi: 10.1016/0306-4522(89)90292-3.

Immunochemical identification of the serine protease inhibitor alpha 1-antichymotrypsin in the brain amyloid deposits of Alzheimer's disease.阿尔茨海默病脑淀粉样沉积物中丝氨酸蛋白酶抑制剂α1-抗糜蛋白酶的免疫化学鉴定

Cell. 1988 Feb 26;52(4):487-501. doi: 10.1016/0092-8674(88)90462-x.

Distribution pattern and functional state of alpha 1-antichymotrypsin in plaques and vascular amyloid in Alzheimer's disease. A immunohistochemical study with monoclonal antibodies against native and inactivated alpha 1-antichymotrypsin.阿尔茨海默病中α1-抗糜蛋白酶在斑块和血管淀粉样蛋白中的分布模式及功能状态。一项使用针对天然和失活α1-抗糜蛋白酶的单克隆抗体的免疫组织化学研究。

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