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压力性尿失禁的药物治疗:对治疗效果的期望

Pharmacologic treatment of stress urinary incontinence: expectations for outcome.

作者信息

Schuessler Bernhard, Baessler Kaven

机构信息

Department of Obstetrics and Gynecology, Cantonal Hospital Lucerne, Lucerne, Switzerland.

出版信息

Urology. 2003 Oct;62(4 Suppl 1):31-8. doi: 10.1016/s0090-4295(03)00797-0.

DOI:10.1016/s0090-4295(03)00797-0
PMID:14550835
Abstract

Several classes of drugs have been investigated for their efficacy in treating stress urinary incontinence (SUI). Despite targeting the mechanisms known to be involved in maintaining continence, few have provided the desired benefits without causing significant adverse effects. Duloxetine, the newest drug to be extensively evaluated for SUI treatment, appears to be both safe and effective. None of the drugs tested thus far has proved to be curative, however. Treatment strategies therefore are aimed at improving the quality of life of patients and should take into account their individual needs and preferences.

摘要

几类药物已被研究其在治疗压力性尿失禁(SUI)方面的疗效。尽管针对已知与维持控尿有关的机制,但很少有药物能在不引起显著不良反应的情况下提供理想的益处。度洛西汀是一种最新被广泛评估用于SUI治疗的药物,似乎既安全又有效。然而,迄今为止测试的药物都未被证明具有治愈性。因此,治疗策略旨在改善患者的生活质量,并且应考虑到他们的个人需求和偏好。

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Duloxetine: in stress urinary incontinence.
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