Sheykholeslami Kianoush, Mohammad Habiby Kermany, Sébastein Schmerber, Kaga Kimitaka
Department of Otolaryngology, Faculty of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-Ku, Tokyo 113-0033, Japan.
Int J Pediatr Otorhinolaryngol. 2003 Oct;67(10):1083-90. doi: 10.1016/s0165-5876(03)00197-6.
Bilateral bone-conducted auditory brainstem responses (BC-ABRs) were recorded in children with atresia of the external auditory canal bilaterally (AECB) in order to compare the response characteristics to normal hearing adults. The binaural interaction component (BIC) of the ABR occurs when the sum of the monaural-evoked ABR amplitudes are different in amplitude when compared to the binaural-evoked ABR amplitude. Previous electrophysiological work from our lab has shown that children with AECB lateralize bone-conducted (BC) sound. Furthermore, we have found in normal-hearing adults that BICs exist using BC clicks. In adults, BC-BIC occurred in the latency region corresponding to waves IV-VI, whereas for children with AECB corresponding peak latencies occurred earlier. Same as normal-hearing adults, BC-ABR IV-V complex peak amplitudes for sum of the BC-monaural right and BC-monaural left ears were different from binaural response amplitude. Individual peak latencies were similar in children with AECB when compared to normal-hearing adults except for shorter latencies for BIC. These results indicate that: (1) BC-BI is present in children with AECB as well as normal-hearing adults; (2) the gross response properties of BIC are similar in children with AECB and normal-hearing adults; (3) fitting of a bilateral BC hearing aid might be a feasible method to optimize binaural hearing and sound lateralization.
为了比较双侧外耳道闭锁（AECB）儿童与正常听力成年人的反应特征，对这些儿童进行了双侧骨导听觉脑干反应（BC-ABR）记录。当单耳诱发的ABR振幅之和与双耳诱发的ABR振幅在幅度上不同时，ABR的双耳相互作用成分（BIC）就会出现。我们实验室之前的电生理研究表明，AECB儿童会使骨导（BC）声音发生侧向化。此外，我们在正常听力的成年人中发现，使用BC短声时存在BIC。在成年人中，BC-BIC出现在对应于波IV-VI的潜伏期区域，而对于AECB儿童，相应的峰值潜伏期出现得更早。与正常听力的成年人一样，但除了BIC潜伏期较短外，AECB儿童的BC-ABR IV-V复合波峰值振幅在BC单耳右耳和BC单耳左耳之和与双耳反应振幅不同。与正常听力的成年人相比，AECB儿童的各个峰值潜伏期相似。这些结果表明：（1）AECB儿童以及正常听力的成年人中都存在BC-BI；（2）AECB儿童和正常听力的成年人中BIC的总体反应特性相似；（3）双侧BC助听器的适配可能是优化双耳听力和声音侧向化的一种可行方法。
