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[钙化牙源性囊肿中的腺样牙源性肿瘤]

[Adenomatoid odontogenic tumor in calcifying odontogenic cyst].

作者信息

Buch R S R, Coerdt W, Wahlmann U

机构信息

Klinik und Poliklinik für Mund-, Kiefer- und Gesichtschirurgie, Klinikum, Johannes-Gutenberg-Universität, Mainz.

出版信息

Mund Kiefer Gesichtschir. 2003 Sep;7(5):301-5. doi: 10.1007/s10006-003-0493-9. Epub 2003 Jul 31.

Abstract

BACKGROUND

Adenomatoid odontogenic tumors (AOT) and calcifying odontogenic cysts (COC, Gorlin's cyst) are rare benign specificities of odontogenic tumors. Most odontogenic tumors are lesions of embryonic odontogenic tissue. Radiographically, odontogenic tumors may mimic an odontogenic follicular cyst.

CASE REPORT

This paper describes the case of an 11-year-old female patient with a remarkable combination of these two entities. The lesions were found at the site of a retained first premolar and a persistent deciduous tooth 84 of the right lower jaw. Without clinical symptoms the tumor had expanded the vestibular cortical bone of the premolar region. Radiographically, the lesion appeared as a typical follicular cyst. During the operation, excochleation of the cyst was performed and the premolar was extracted. Finally, the epithelium of the cyst was treated by curettage. The histologic specimen revealed the diagnosis of an adenomatoid odontogenic tumor (AOT) in a calcifying odontogenic cyst (COC).

DISCUSSION

The described case shows that symptoms of odontogenic tumors are usually nonspecific. For that reason one should always take a biopsy for histological investigation when patients present atypical cysts of the jaw. In rare cases even malignant odontogenic neoplasms could occur.

摘要

背景

腺样牙源性肿瘤(AOT)和牙源性钙化囊肿(COC,戈林囊肿)是牙源性肿瘤中罕见的良性特异性病变。大多数牙源性肿瘤是胚胎牙源性组织的病变。在影像学上,牙源性肿瘤可能类似牙源性滤泡囊肿。

病例报告

本文描述了一名11岁女性患者同时患有这两种病变的显著病例。病变位于右下颌第一乳磨牙滞留及恒牙84的部位。该肿瘤在无临床症状的情况下已侵犯前磨牙区的前庭皮质骨。影像学上,病变表现为典型的滤泡囊肿。手术中,刮除囊肿并拔除前磨牙。最后,对囊肿上皮进行刮治。组织学标本显示为牙源性钙化囊肿(COC)内的腺样牙源性肿瘤(AOT)。

讨论

所述病例表明牙源性肿瘤的症状通常不具有特异性。因此,当患者出现颌骨非典型囊肿时,应始终进行活检以进行组织学检查。在罕见情况下,甚至可能发生恶性牙源性肿瘤。

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