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动脉粥样硬化患者血浆中的游离氨基酸(作者译)

[Free amino-acids of the plasma in atherosclerotic patients (author's transl)].

作者信息

Oberwittler W, Brennhaussen B, Rauen H, Hauss W H

出版信息

Aktuelle Gerontol. 1977 Jan;7(1):47-43.

PMID:14552
Abstract

18 free amino-acids have been valuated in a group of patients recovering from myocardial infarction dating more than one year back and in another group of healthy active athlets. In the group of the ill persons the mean values of the following amino-acids were significantly higher: Arginine, asparagine-acid, phenylalanine, valine, lysine, serine, threonine, leucine, proline and tyrosine. While in the group of the healthy persons the following amino - acids proved to have significantly higher values: alpha -- aminobutter-acid, glycine and cystine. No significant differences between the mean values of both groups were to be found of the following amino - acids: Alanine, methionine, ornithine, isoleucine and histidine. In the group of the patients correlations of the free amino acids to both serumlipids and blood -- glucose could be calculated with significant results in a certain number of amino-acids. The results may suppose that the changes in the metabolism of atherosclerotic patients do not only effect the lipids and carbohydrates, but as well the free amino-acids.

摘要

对一组一年多前心肌梗死康复患者和另一组健康活跃的运动员进行了18种游离氨基酸的评估。在患病组中,以下氨基酸的平均值显著更高:精氨酸、天冬氨酸、苯丙氨酸、缬氨酸、赖氨酸、丝氨酸、苏氨酸、亮氨酸、脯氨酸和酪氨酸。而在健康组中,以下氨基酸的值显著更高:α-氨基丁酸、甘氨酸和胱氨酸。两组之间以下氨基酸的平均值没有显著差异:丙氨酸、蛋氨酸、鸟氨酸、异亮氨酸和组氨酸。在患者组中,可以计算游离氨基酸与血脂和血糖的相关性,在一定数量的氨基酸中结果显著。结果可能表明,动脉粥样硬化患者代谢的变化不仅影响脂质和碳水化合物,也影响游离氨基酸。

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