Wilk Aldona, Kazimierczuk Krystyna
Kliniki Okulistycznej Wojskowego Instytutu Medycznego w Warszawie.
Klin Oczna. 2003;105(3-4):217-20.
Anterior ischemic optic neuropathy (AION) is the result of infarct of the optic nerve head, caused by occlusion of one or more short posterior ciliary arteries. On the base of different treatment and prognosis there are two forms of AION: arteritic and non-arteritic (NAION). Arteritic ischemic optic neuropathy is caused by giant cell arteritis (GCA). The most typical symptoms are: the sudden and deep vision loss and headache, scalp tenderness, jaw claudication, muscle ache, fever and weight loss. The ophthalmologist usually finds an abnormal pupil, a swollen optic nerve (disc edema), and peripheral or central vision loss (or both). About 70% of cases are not progressive, i.e., the vision remains stable, but reduced. The ESR is usually markedly elevated. Temporal artery biopsy is useful in confirming the diagnosis of arteritic AION. Treatment involves the immediate administration of systemic steroids. Though steroid therapy rarely results in the return of vision, it is beneficial in protecting the fellow eye from vision loss and improving long-term systemic health.
前部缺血性视神经病变(AION)是视神经乳头梗死的结果,由一支或多支睫状后短动脉阻塞引起。基于不同的治疗方法和预后情况,AION有两种类型:动脉炎性和非动脉炎性(非动脉炎性前部缺血性视神经病变,NAION)。动脉炎性缺血性视神经病变由巨细胞动脉炎(GCA)引起。最典型的症状是:突然且严重的视力丧失以及头痛、头皮触痛、颌部间歇性运动障碍、肌肉疼痛、发热和体重减轻。眼科医生通常会发现瞳孔异常、视神经肿胀(视盘水肿)以及周边或中心视力丧失(或两者皆有)。约70%的病例不会进展,即视力保持稳定,但会下降。红细胞沉降率(ESR)通常会显著升高。颞动脉活检有助于确诊动脉炎性AION。治疗包括立即给予全身性类固醇药物。虽然类固醇疗法很少能使视力恢复,但有助于保护对侧眼避免视力丧失,并改善长期全身健康状况。