最终诊断为导管原位癌患者的腋窝淋巴结转移情况。
Axillary lymph node metastases in patients with a final diagnosis of ductal carcinoma in situ.
作者信息
Kelly Tricia A, Kim Julian A, Patrick Rebecca, Grundfest Sharon, Crowe Joseph P
机构信息
Cleveland Clinic Breast Center, Cleveland Clinic Foundation, Department of General Surgery, A-80, 9500 Euclid Ave, Cleveland, OH 44195, USA.
出版信息
Am J Surg. 2003 Oct;186(4):368-70. doi: 10.1016/s0002-9610(03)00276-9.
BACKGROUND
Recent studies report the incidence of axillary metastases in patients with ductal carcinoma in-situ (DCIS) approaches 13%. The purpose of this study was to define the incidence of axillary micrometastases in patients with pure DCIS before and after the introduction of sentinel lymph node biopsy.
METHODS
Patients with a final diagnosis of DCIS form the basis of this study. Data were entered prospectively into an Institutional Review Board approved Oracle database from January 1997 through July 2002.
RESULTS
One hundred and thirty-four patients had lymph nodes evaluated. Ninety-eight percent of patients had no evidence of metastatic disease and 2% were found to have micrometastases. This was consistent in those who had level I or II lymph node sampling or both and those who had lymphatic mapping and a sentinel lymph node biopsy procedure.
CONCLUSIONS
These data do not support axillary lymph node removal of any type in patients with pure DCIS.
背景
近期研究报告称，导管原位癌（DCIS）患者腋窝转移的发生率接近13%。本研究的目的是确定前哨淋巴结活检引入前后纯DCIS患者腋窝微转移的发生率。
方法
最终诊断为DCIS的患者构成了本研究的基础。数据从1997年1月至2002年7月前瞻性地录入经机构审查委员会批准的甲骨文数据库。
结果
134例患者接受了淋巴结评估。98%的患者没有转移疾病的证据，2%的患者被发现有微转移。在进行I级或II级淋巴结采样或两者都进行的患者以及进行淋巴管造影和前哨淋巴结活检手术的患者中，情况是一致的。
结论
这些数据不支持对纯DCIS患者进行任何类型的腋窝淋巴结清扫。
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