Prakash K M, Raymond A A
Department of Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Yaacob Latiff, 56000 Cheras, Kuala Lumpur.
Med J Malaysia. 2003 Mar;58(1):69-78.
Bell's palsy is a common neurological problem causing considerable loss of self-esteem among patients. A prospective observational study was conducted to determine the short-term outcome of Bell's palsy at 1 month and 2 months after the onset and the relationship between these outcomes with facial nerve degeneration. We also determined if gender, age, diabetes, systolic and diastolic blood pressure influence the severity of facial nerve degeneration and the clinical outcome at 2 months after the onset. After clinically grading the newly diagnosed unilateral Bell's palsy patients using the House-Brackmann facial nerve grading system, nerve conduction studies of the facial nerve were done to determine the severity of facial nerve degeneration. The recovery of the facial paralysis was clinically graded again at the end of 1 month and 2 months from the onset. A total of 37 patients were recruited. There was a strong positive correlation between facial nerve degeneration and the clinical outcome of Bell's palsy at 1 month (r = 0.794; p < 0.0005) and 2 months (r = 0.732; p < 0.0005) after the onset. There was no significant correlation between either the facial nerve degeneration or the clinical outcome at 2 months with the patients' age (p = 0.288 and p = 0.799 respectively), systolic blood pressure (p = 0.425 and p = 0.933 respectively) or diastolic blood pressure (p = 0.243 and p = 0.579 respectively). Neither the severity of facial nerve degeneration nor the clinical outcome at 2 months were significantly different between male and female patients (p = 0.460 and p = 0.725 respectively) or diabetic and non-diabetic patients (p = 0.655 and p = 0.655 respectively).
贝尔面瘫是一种常见的神经问题,会给患者带来相当大的自尊丧失。进行了一项前瞻性观察研究,以确定贝尔面瘫发病后1个月和2个月时的短期预后,以及这些预后与面神经变性之间的关系。我们还确定了性别、年龄、糖尿病、收缩压和舒张压是否会影响面神经变性的严重程度以及发病后2个月时的临床预后。使用House-Brackmann面神经分级系统对新诊断的单侧贝尔面瘫患者进行临床分级后,对面神经进行神经传导研究以确定面神经变性的严重程度。面瘫恢复情况在发病后1个月和2个月结束时再次进行临床分级。共招募了37名患者。发病后1个月(r = 0.794;p < 0.0005)和2个月(r = 0.732;p < 0.0005)时,面神经变性与贝尔面瘫的临床预后之间存在强正相关。面神经变性或2个月时的临床预后与患者年龄(分别为p = 0.288和p = 0.799)、收缩压(分别为p = 0.425和p = 0.933)或舒张压(分别为p = 0.243和p = 0.579)之间均无显著相关性。男性和女性患者(分别为p = 0.460和p = 0.725)或糖尿病患者和非糖尿病患者(分别为p = 0.655和p = 0.655)在2个月时面神经变性的严重程度和临床预后均无显著差异。