Parazzini Fabio
Instituto di Ricerche Farmacologiche Mario Negri, Via Eritrea 62, 20157 Milan, Italy.
Eur J Obstet Gynecol Reprod Biol. 2003 Nov 10;111(1):65-7. doi: 10.1016/s0301-2115(03)00198-2.
The frequency of endometriotic lesions in the right and left hemipelvis was analysed in 856 women with endometriosis. Eligible for the study were women with primary or secondary sterility, chronic pelvic pain, fibroids or benign ovarian cysts requiring laparoscopy or laparotomy consecutively observed between May 1991 and July 1992 in 23 obstetric and gynecology departments in Italy. Women with a previous diagnosis of endometriosis were excluded. A total of 3684 women entered the study. Of those, 856 had endometriosis and are considered in the present analysis.
Five hundred and ninety four had bilateral lesions (including both ovarian and peritoneal lesions). Of the 262 women with unilateral lesions, 118 (45%, 95% confidence intervals (CI) 38-54) had the lesions in the right side of the pelvis and 144 (55%) in the left one.
From an anatomical point of view, these findings support the transplantation therapy in the pathogenesis of endometriosis.
对856例子宫内膜异位症患者左右半盆腔内子宫内膜异位病灶的发生率进行分析。本研究的入选对象为1991年5月至1992年7月期间，在意大利23个妇产科科室连续接受腹腔镜检查或剖腹手术的原发性或继发性不孕、慢性盆腔疼痛、子宫肌瘤或良性卵巢囊肿患者。既往诊断为子宫内膜异位症的女性被排除在外。共有3684名女性参与本研究。其中，856例患有子宫内膜异位症，并纳入本分析。
594例有双侧病灶（包括卵巢和腹膜病灶）。在262例单侧病灶患者中，118例（45%，95%置信区间（CI）38 - 54）病灶位于盆腔右侧，144例（55%）位于左侧。
从解剖学角度来看，这些发现支持了子宫内膜异位症发病机制中的移植理论。
