Obray Rick, Clatterbuck Richard, Olvi Alessandro, Tamargo Rafael, Murphy Kieran J, Gailloud Philippe
Division of Interventional Neuroradiology, Johns Hopkins Hospital, Baltimore, MD 21287, USA.
AJNR Am J Neuroradiol. 2003 Oct;24(9):1811-3.
Two cases of angiographically and surgically documented de novo intracranial aneurysm formation are reported. The first patient, a 32-year-old woman, developed two new aneurysms within a 6-month period, and the second patient, a 27-year-old woman, developed two new aneurysms within a 22-month period. In both patients, the new aneurysms were symptomatic, causing stroke and subarachnoid hemorrhage, respectively. The development of aneurysms de novo over such a short period of time has important implications for periodic imaging in patients considered to be at high risk for intracranial aneurysm formation.