Arslanoglu Atilla, Cirak Bayram, Horska Alena, Okoh James, Tihan Tarik, Aronson Leslie, Avellino Anthony M, Burger Peter C, Yousem David M
Department of Radiology, Johns Hopkins University, Baltimore, MD 21287, USA.
AJNR Am J Neuroradiol. 2003 Oct;24(9):1906-8.
Pilomyxoid astrocytoma (PMA) is a recently described tumor that typically occurs in the chiasmatic-hypothalamic region in young children and has unique histopathologic and clinical characteristics. These tumors have been previously diagnosed as pilocytic astrocytoma (PA). PMA appears to have a higher rate of recurrence and CSF dissemination than typical PA.
We analyzed MR findings in four patients with PMA and compared them with those of typical chiasmatic-hypothalamic PA.
MR findings of PMA were chiasmatic or hypothalamic enhancing solid tumor with hydrocephalus, highly homogeneous T2 signal intensity that extended into the deep white and gray matter, and CSF dissemination.
Larger series are needed before the MR imaging findings of chiasmatic or hypothalamic enhancing solid tumor with hydrocephalus, highly homogeneous T2 signal intensity extending into the deep white and gray matter, and CSF dissemination can be used in the differential diagnosis of such tumors.
毛黏液样星形细胞瘤(PMA)是一种最近描述的肿瘤,通常发生于幼儿的视交叉 - 下丘脑区域,具有独特的组织病理学和临床特征。这些肿瘤此前被诊断为毛细胞型星形细胞瘤(PA)。与典型的PA相比,PMA似乎具有更高的复发率和脑脊液播散率。
我们分析了4例PMA患者的磁共振成像(MR)表现,并将其与典型的视交叉 - 下丘脑PA患者的表现进行比较。
PMA的MR表现为视交叉或下丘脑强化实性肿瘤伴脑积水,T2信号高度均匀,延伸至深部白质和灰质,以及脑脊液播散。
在具有脑积水、延伸至深部白质和灰质的高度均匀T2信号以及脑脊液播散的视交叉或下丘脑强化实性肿瘤的MR成像表现可用于此类肿瘤的鉴别诊断之前,需要更大样本量的研究。