子宫内暴露于己烯雌酚的女性孕早期妊娠子宫自发性破裂。病例报告。
Spontaneous rupture of a first-trimester gravid uterus in a woman exposed to diethylstilbestrol in utero. A case report.
作者信息
Porcu Géraldine, Courbière Blandine, Sakr Rita, Carcopino Xavier, Gamerre Marc
机构信息
Department of Obstetrics and Gynecology, Hôpitaux de Marseille, Marseille, France.
出版信息
J Reprod Med. 2003 Sep;48(9):744-6.
BACKGROUND
Poor reproductive outcome was well documented in several studies of women exposed to diethylstilbestrol in utero. Spontaneous rupture of an unscarred uterus is rare and very uncommon in the first trimester of pregnancy.
CASE
Spontaneous rupture of the uterus was diagnosed in a 28-year-old nullipara who developed acute abdominal pain at 12 weeks' gestation. She was known to have been exposed to diethylstilbestrol in utero. Laparotomy revealed the rupture in the anterior fundal area of the uterus. Both tubes were normal.
CONCLUSION
Several spontaneous ruptures have been described, but this is the first case of first-trimester spontaneous rupture of an unscarred uterus in a diethylstilbestrol-exposed woman.
背景
多项针对子宫内暴露于己烯雌酚的女性的研究充分记录了不良生殖结局。未瘢痕化子宫的自发性破裂很少见，在妊娠早期极为罕见。
病例
一名28岁未孕女性在妊娠12周时出现急性腹痛，被诊断为子宫自发性破裂。已知她在子宫内曾暴露于己烯雌酚。剖腹探查发现子宫前底部区域破裂。双侧输卵管正常。
结论
已有数例自发性子宫破裂的报道，但这是首例子宫内暴露于己烯雌酚的女性在妊娠早期出现未瘢痕化子宫自发性破裂的病例。
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