[The new agent G-1724: synthesis and test on murine models of trichuriasis and trichinosis].
作者信息
Dobrovinskaia N A, Trusov S N, Fedianina L V, Veretennikova N L, Sevbo D P, Mikhaĭlitsyn F S
出版信息
Med Parazitol (Mosk). 2003 Jul-Sep(3):40-1.
PMID:14564844
Abstract
To search for new antihelminthics, the new compound N-[3-chloro-4-[(1-ethyl-2-benzimidazolyl) thio]phenyl]-2-hydroxy-3,5-dibromobenzamide (the agent G-1724) was synthesized and tested by using the models of trichocephaliasis (Trichocephalus muris) and trichinosis (Trichinella spiralis). The tests demonstrated that this agent had an nematocidal effect (71-78%).
摘要
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