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[米非司酮用于医学终止妊娠——舍巴医疗中心的初步经验]

[Medical termination of pregnancy with mifepristone--initial experience at the Sheba Medical Center].

作者信息

Machtinger R, Goldenberg M, Soriano D, Zolti M, Atlas M, Seidman D S

机构信息

Department of Obstetrics and Gynecology, Chaim Sheba Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

出版信息

Harefuah. 2003 Oct;142(10):666-8, 719.

Abstract

OBJECTIVE

To assess the early implementation of medical termination of pregnancy as an alternative treatment option for women in early pregnancy who wish to avoid a surgical procedure.

METHODS

The use of mifepristone (RU-486) for medical termination was recently approved in Israel. We performed a prospective follow-up study of the 189 women who underwent medical termination of pregnancy with mifepristone and misoprostol in our center between January 2000 and April 2001.

RESULTS

Complete outcome data was obtained for 176 women. Within this group 152 women (86.4%) did not need any surgical procedure to complete the abortion. Uterine curettage was performed in 17 (9.6%) and operative hysteroscopy in 7 (4.0%) of the women because of incomplete abortion or suspected residua of pregnancy.

CONCLUSION

Medical abortion offers an efficient and safe treatment option to women who wish to avoid surgical evacuation.

摘要

目的

评估药物流产作为早期妊娠女性避免手术终止妊娠的一种替代治疗方案的早期实施情况。

方法

米非司酮(RU - 486)用于药物流产最近在以色列获得批准。我们对2000年1月至2001年4月间在我们中心接受米非司酮和米索前列醇药物流产的189名女性进行了前瞻性随访研究。

结果

获得了176名女性的完整结局数据。在这组中,152名女性(86.4%)无需任何手术操作即可完成流产。17名(9.6%)女性因流产不全或怀疑有妊娠残留物接受了刮宫术,7名(4.0%)女性接受了宫腔镜手术。

结论

药物流产为希望避免手术清宫的女性提供了一种有效且安全的治疗选择。

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