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磷二酰胺作为抗病毒核苷的前药。

Phosphorodiamides as prodrugs for antiviral nucleosides.

作者信息

Shipitsyn Alexander V, Zakirova Natalya F, Belanov Evgeny F, Pronyaeva Tatyana R, Fedyuk Nina V, Kukhanova Marina K, Pokrovsky Andrey G

机构信息

Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.

出版信息

Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):963-6. doi: 10.1081/NCN-120022696.

Abstract

New phosphorodiamides of modified nucleoside monophosphates were synthesized and their antiviral properties were evaluated.

摘要

合成了修饰核苷单磷酸的新型磷二酰胺,并对其抗病毒特性进行了评估。

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