Leonard P, Kröschel R, Seela F
Laboratorium für Organische und Bioorganische Chemie, Institut für Chemie, Universität Osnabrück, Osnabrück, Germany.
Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):1235-7. doi: 10.1081/NCN-120022844.
The H-phosphonate and the phosphoramidite of N7-2'-deoxyisoguanosine (2) were prepared and incorporated into oligonucleotide duplexes. Their base pairing properties were investigated and compared with those of the parent purine nucleosides.
制备了N7 - 2'-脱氧异鸟苷(2)的H-膦酸酯和亚磷酰胺,并将其掺入寡核苷酸双链体中。研究了它们的碱基配对性质,并与母体嘌呤核苷的碱基配对性质进行了比较。