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鸟嘌呤核苷被二甲基二氧杂环丙烷氧化为4-脒基氨基甲酰基-5-羟基咪唑。

Oxidation of guanine nucleosides to 4-amidinocarbamoyl-5-hydroxyimidazoles by dimethyldioxirane.

作者信息

Davies R Jeremy H, Stevenson Clarke, Kumar Shiv, Lyle Jason, Cosby Lisa, Malone John F, Boyd Derek R, Sharma Narain D, Hunter Ann P, Stein Bridget K

机构信息

School of Biology and Biochemistry, Queen's University, Belfast, Northern Ireland.

出版信息

Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):1355-7. doi: 10.1081/NCN-120022964.

DOI:10.1081/NCN-120022964
PMID:14565417
Abstract

Final oxidation products generated from guanosine and 2'-deoxyguanosine by reaction with dimethyldioxirane have been identified as 4-amidinocarbamoyl-5-hydroxyimidazoles.

摘要

鸟苷和2'-脱氧鸟苷与二甲基二氧杂环丙烷反应生成的最终氧化产物已被鉴定为4-脒基氨基甲酰基-5-羟基咪唑。

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