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信使核糖核酸5'帽类似物的偏摩尔体积

Partial molar volumes of mRNA 5' cap analogues.

作者信息

Szymanski Jedrzej, Stepinski Janusz, Poznanski Jaroslaw, Darzynkiewicz Edward, Zielenkiewicz Wojciech, Stolarski Ryszard

机构信息

Department of Biophysics, Institute of Experimental Physics, Warsaw University, Warszawa, Poland.

出版信息

Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):1553-6. doi: 10.1081/NCN-120023032.

DOI:10.1081/NCN-120023032
PMID:14565464
Abstract

Partial molar volumes in aqueous solution of eleven selected 7-methylguanine cap-analogues and their guanine counterparts were determined by means of density measurements. Hydrophobicity of the investigated compounds regarding their structural features was analysed within the framework of the solute-solvent interaction model, based on the relative density of the molecular solvation shell.

摘要

通过密度测量确定了十一种选定的7-甲基鸟嘌呤帽类似物及其鸟嘌呤对应物在水溶液中的偏摩尔体积。基于分子溶剂化壳层的相对密度，在溶质-溶剂相互作用模型的框架内分析了所研究化合物相对于其结构特征的疏水性。

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