使用支气管内超声测量哮喘患者的上皮下厚度：一例病例报告。

Measuring subepithelial thickness using endobronchial ultrasonography in a patient with asthma: a case report.

作者信息

Yamasaki A, Tomita K, Sano H, Watanabe M, Makino H, Kurai J, Hitsuda Y, Shimizu E

机构信息

Third Department of Internal Medicine, Faculty of Medicine, Tottori University, 36-1 Nishi-machi, Yonago-shi, Tottori-ken 683-8504, Japan.

出版信息

Lung. 2003;181(3):115-20. doi: 10.1007/s00408-003-1012-3.

DOI:10.1007/s00408-003-1012-3

PMID:14565685

Abstract

The chronic inflammation of bronchial asthma is characterized by swelling of the subepithelial mucosa. However, it is difficult to assess subepithelial edema clinically. We report the case of a patient with asthma whose subepithelial edema was evaluated by endobronchial ultrasonography. Receiving montelukast 10 mg/day for 2 weeks, a 42-year-old man with mild, persistent asthma had his symptoms controlled by beta2-inhalation alone. Pretreatment endobronchial ultrasonography revealed subepithelial thickening in the right main stem bronchus, with a low absorption area suggestive of edema. Two weeks of montelukast therapy diminished the amount of subepithelial edema. Endobronchial ultrasonography is a promising technique for determining subepithelial edema in the asthmatic airway.

摘要

支气管哮喘的慢性炎症特征为上皮下黏膜肿胀。然而，临床上很难评估上皮下水肿情况。我们报告1例哮喘患者，其上皮下水肿通过支气管内超声进行评估。一名42岁轻度持续性哮喘男性患者，每天服用孟鲁司特10 mg，持续2周，其症状仅通过β2吸入剂即可得到控制。治疗前支气管内超声显示右主支气管上皮下增厚，存在提示水肿的低吸收区。孟鲁司特治疗2周后，上皮下水肿量减少。支气管内超声是一种用于确定哮喘气道上皮下水肿的有前景的技术。