Evrard S, Marescaux J
Service d'Urgence, Hôpital Civil, Strasbourg.
Ann Chir. 1992;46(7):561-9.
The "revisionist" approach to therapy of gastric cancer needs a previous demonstration of the qualitative comparability of Japanese and western treatments of gastric adenocarcinoma. Early gastric cancer is far more common in Japanese than in Occidentals, but its character is the same, and for identical stages and treatments, the prognosis is the same. But many western studies show serious methodological deficiencies (staging, anatomopathological examination...), as well as a serious lack of interest in adjuvant therapy, a potential source of progress. We propose a 4-point therapeutic approach inspired by the Japanese example: a greater methodological rigor, standardization of lymphadenectomies, the definition of therapeutic subgroups to receive optimal treatments, the development of new adjuvant treatments.
胃癌治疗的“修正主义”方法需要事先证明日本和西方对胃腺癌治疗在质量上的可比性。早期胃癌在日本人中比在西方人中更为常见,但其特征是相同的,并且对于相同的分期和治疗,预后也是相同的。但是许多西方研究显示出严重的方法学缺陷(分期、解剖病理学检查……),以及对辅助治疗严重缺乏兴趣,而辅助治疗是潜在的进展来源。我们提出一种受日本实例启发的四点治疗方法:更高的方法学严谨性、淋巴结清扫的标准化、定义接受最佳治疗的治疗亚组、开发新的辅助治疗方法。