Khan Alamgir, Williams Keith, Nevalainen Helena
Proteome Systems Ltd., 1/35-41 Waterloo Road, 2113, North Ryde, NSW, Australia.
FEMS Microbiol Lett. 2003 Oct 10;227(1):107-11. doi: 10.1016/S0378-1097(03)00654-2.
Paecilomyces lilacinus is a nematophagous fungus currently developed as a biological control agent. In order to evaluate potential toxin production, culture extract and concentrated culture supernatant of P. lilacinus strain 251 were tested against Gram-negative and Gram-positive bacteria. High-performance liquid chromatography analysis was carried out to compare the chromatograms of P. lilacinus strain 251 with the chromatogram of known paecilotoxin. It was found that the 251 strain of P. lilacinus did not produce detectable levels of paecilotoxin or other toxins with antimicrobial activity.
淡紫拟青霉是一种目前正作为生物防治剂开发的食线虫真菌。为了评估其潜在的毒素产生情况，对淡紫拟青霉251菌株的培养提取物和浓缩培养上清液进行了针对革兰氏阴性菌和革兰氏阳性菌的测试。进行了高效液相色谱分析，以比较淡紫拟青霉251菌株的色谱图与已知拟青霉素的色谱图。结果发现，淡紫拟青霉251菌株未产生可检测水平的拟青霉素或其他具有抗菌活性的毒素。
