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NOD2/CARD15 and the Paneth cell: another piece in the genetic jigsaw of inflammatory bowel disease.

作者信息

Aldhous M C, Nimmo E R, Satsangi J

机构信息

Edinburgh University Medical School, Gastrointestinal Unit, Western General Hospital, Edinburgh, UK.

出版信息

Gut. 2003 Nov;52(11):1533-5. doi: 10.1136/gut.52.11.1533.

DOI:10.1136/gut.52.11.1533
PMID:14570717
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1773871/
Abstract
摘要

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本文引用的文献

1
Expression of NOD2 in Paneth cells: a possible link to Crohn's ileitis.潘氏细胞中NOD2的表达：与克罗恩病性回肠炎的可能联系。
Gut. 2003 Nov;52(11):1591-7. doi: 10.1136/gut.52.11.1591.
2
Crohn's disease and the NOD2 gene: a role for paneth cells.克罗恩病与NOD2基因：潘氏细胞的作用
Gastroenterology. 2003 Jul;125(1):47-57. doi: 10.1016/s0016-5085(03)00661-9.
3
An analysis of factors influencing short-term and sustained response to infliximab treatment for Crohn's disease.影响克罗恩病英夫利昔单抗治疗短期及持续反应的因素分析。
Aliment Pharmacol Ther. 2003 Jun 15;17(12):1451-7. doi: 10.1046/j.1365-2036.2003.01574.x.
4
Card15 gene overexpression in mononuclear and epithelial cells of the inflamed Crohn's disease colon.炎症性克罗恩病结肠的单核细胞和上皮细胞中Card15基因过表达。
Gut. 2003 Jun;52(6):840-6. doi: 10.1136/gut.52.6.840.
5
Association of NOD2 with Crohn's disease in a homogenous Irish population.在爱尔兰同质人群中NOD2与克罗恩病的关联。
Eur J Hum Genet. 2003 Mar;11(3):237-44. doi: 10.1038/sj.ejhg.5200954.
6
TNF-alpha and IFN-gamma regulate the expression of the NOD2 (CARD15) gene in human intestinal epithelial cells.肿瘤坏死因子-α和干扰素-γ调节人肠上皮细胞中NOD2（CARD15）基因的表达。
Gastroenterology. 2003 Apr;124(4):1001-9. doi: 10.1053/gast.2003.50157.
7
CARD15/NOD2 functions as an antibacterial factor in human intestinal epithelial cells.CARD15/NOD2在人类肠道上皮细胞中作为一种抗菌因子发挥作用。
Gastroenterology. 2003 Apr;124(4):993-1000. doi: 10.1053/gast.2003.50153.
8
Toll-like receptors and their function in innate and adaptive immunity.Toll样受体及其在固有免疫和适应性免疫中的功能。
Int Arch Allergy Immunol. 2003 Mar;130(3):180-92. doi: 10.1159/000069517.
9
CARD15/NOD2 gene variants are associated with familially occurring and complicated forms of Crohn's disease.CARD15/NOD2基因变异与家族性发生的复杂型克罗恩病相关。
Gut. 2003 Apr;52(4):558-62. doi: 10.1136/gut.52.4.558.
10
Gene-environment interaction modulated by allelic heterogeneity in inflammatory diseases.炎症性疾病中由等位基因异质性调节的基因-环境相互作用。
Proc Natl Acad Sci U S A. 2003 Mar 18;100(6):3455-60. doi: 10.1073/pnas.0530276100. Epub 2003 Mar 7.