Cardiac failure after initiation of insulin treatment in diabetic patients with beta-thalassemia major.
作者信息
Konrad Daniel, Daneman Denis, Kirby Melanie, Wherrett Diane
机构信息
Division of Endocrinology, Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto, Ontario M5G 1X8, Canada.
出版信息
J Pediatr. 2003 Oct;143(4):541-2. doi: 10.1067/S0022-3476(03)00414-1.
Abstract
Diabetes mellitus is a complication of beta-thalassemia major. Two patients are described who developed severe cardiac failure after initiation or intensification of insulin treatment. We hypothesize that insulin-induced fluid retention combined with reduced cardiac reserve was responsible for the cardiac failure. Careful initiation of insulin treatment in these patients is important.
摘要
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