Datz F L, Gabor F V, Christian P E, Gullberg G T, Menzel C E, Morton K A
Division of Nuclear Medicine, University of Utah School of Medicine, Salt Lake City 84132.
J Digit Imaging. 1992 Nov;5(4):209-22. doi: 10.1007/BF03167802.
The use of computer-assisted diagnosis has become widespread in cardiac nuclear medicine. Quantitative programs are commercially available for ventriculography, phase analysis, and thallium 201 perfusion studies. The goal of these programs is to eliminate interobserver variability by objectively analyzing the studies without causing a loss of accuracy. In addition, by using quantitative data not apparent on visual inspection, some programs attempt to increase sensitivity for disease above that possible by the visual reading of images. Programs that analyze perfusion studies to detect coronary artery disease have received the most interest. Results have varied, but sensitivities as high as 95% have been reported. This review discusses the techniques of computer-assisted diagnosis for thallium 201 myocardial-perfusion studies. The circumferential and washout profile methods are discussed in detail.
计算机辅助诊断在心脏核医学中的应用已十分广泛。用于心室造影、相位分析和铊201灌注研究的定量程序已有商业产品。这些程序的目标是通过客观分析研究来消除观察者间的差异，同时又不损失准确性。此外，通过使用视觉检查中不明显的定量数据，一些程序试图提高对疾病的敏感度，使其高于通过图像视觉解读所能达到的水平。用于检测冠状动脉疾病的灌注研究分析程序最受关注。结果各不相同，但有报道称敏感度高达95%。本文综述了铊201心肌灌注研究的计算机辅助诊断技术。详细讨论了圆周和洗脱曲线方法。
